Cheng Lyu

The paper introduces endocytome profiling to map cell-surface protein dynamics in developing olfactory receptor neurons, revealing how endocytosis regulates axon pruning and targeting.

The paper shows that dimensionality reduction simplifies synaptic partner matching in the fly antennal lobe by reducing a 3D search problem to a 1D trajectory.

The paper shows that altering a combination of cell-surface proteins in Drosophila olfactory neurons can switch their synaptic connections to different projection neuron types, revealing a combinatorial code for circuit assembly.

The paper identifies three CSP pairs mediating repulsive interactions that prevent non-cognate synaptic connections in Drosophila olfactory circuits.

This study identifies the intracellular signaling pathway of teneurins in synaptic partner matching using Drosophila models.

This study investigates how projection neurons in Drosophila establish wiring specificity in the olfactory map through lineage, birth order, and dynamic dendrite remodeling during development.

The paper identifies two cell types in Drosophila that encode body-centric movement signals and shows how they transform these signals into world-centric coordinates for navigation.

The paper identifies a neuronal circuit in Drosophila that performs vector arithmetic to compute an allocentric traveling-direction signal.