Colleen N. McLaughlin

This study identifies the distinct roles of Rab5 and Rab11 in regulating neural circuit assembly through endosome-mediated trafficking.

The paper introduces endocytome profiling to map cell-surface protein dynamics in developing olfactory receptor neurons, revealing how endocytosis regulates axon pruning and targeting.

This study evolves a laccase enzyme for cell surface labeling and EM, showing it can map T cell surface changes and visualize cell features without toxic H2O2.

The paper shows that dimensionality reduction simplifies synaptic partner matching in the fly antennal lobe by reducing a 3D search problem to a 1D trajectory.

This study identifies the intracellular signaling pathway of teneurins in synaptic partner matching using Drosophila models.

The paper creates a single-cell transcriptomic atlas of the adult fruit fly, identifying over 250 cell types and analyzing gene signatures and sexual dimorphism across tissues.

The paper generates single-cell transcriptomes of Drosophila olfactory receptor neurons across development and adulthood, revealing stable receptor expression and cell-type-specific transcriptomic features.

The paper analyzes single-cell transcriptomes of Drosophila olfactory projection neurons across developmental stages to identify transcriptomic changes and cellular diversity patterns.

The paper profiles cell-surface proteomes in Drosophila olfactory neurons across development, identifying new regulators of neural circuit assembly.