Author

Kinga Winczura

University of ManchesterORCID 0000-0003-2958-8728Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

Pawel GrzechnikiD· 3 shared Daniel HebenstreitiD· 2 shared Matt JonesiD· 2 shared Monika ŚledziowskaiD· 2 shared Erich KolleriD· 1 shared Hannah E. MischoiD· 1 shared Holly FagarasaniD· 1 shared Hurmuz CeylaniD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMolecular Biology

Pawel GrzechnikORCID

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3 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedOct 9, 2026

Antisense oligonucleotides targeting transcription termination windows disrupt mRNA 3' end processing and decrease gene expression

Kinga Winczura, Lars Joenson, Erich Koller…·Lukasz Jan Kielpinski

This study shows that antisense oligonucleotides targeting transcription termination windows can decrease gene expression by disrupting mRNA 3' end processing and causing off-target effects.

2 citationstop 5%

multiomeexperimental assay

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Molecular BiologybioRxivPreprintJun 20, 2021

RPRD Proteins Control Transcription in Human Cells

Kinga Winczura, Hurmuz Ceylan, Monika Śledziowska…·Pawel Grzechnik

This study identifies RPRD proteins as negative regulators of transcription in human cells, showing their inverse correlation with RNA accumulation and their role in forming complexes with Pol II.

4 citations

humanexperimental assay

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Molecular BiologyHuman Molecular GeneticsPeer-reviewedJan 1, 2021

Non-coding RNAs Associated with Prader-Willi Syndrome Regulate Transcription of Neurodevelopmental Genes in Human Induced Pluripotent Stem Cells

Monika Śledziowska, Kinga Winczura, Matt Jones…·Pawel Grzechnik

The paper investigates how non-coding RNAs from the Prader-Willi syndrome locus regulate gene expression in human iPSCs, showing their role in neurodevelopmental processes.

22 citations

humanbulk RNA-seq

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