Devid Damiani

This study investigates the effects of HPDL variants on cortical development, finding synaptic impairment, glial loss, and reactivation of developmental programs in HPDL-deficient cultures.

This study shows HPDL is essential for cortical development by regulating mitochondrial function and neurogenesis, with implications for SPG83 pathology and potential antioxidant therapies.

This study identifies SINEUP RNAs with Internal Ribosomal Entry Site (IRES) sequences as effector domains, enhancing translation of target mRNAs through both linear and circular transcripts.

This study shows Pgbd5 is essential for neuronal differentiation and radial migration in mouse corticogenesis, with effects on DNA double-strand breaks and gene expression.

This study shows that DIAPH3 deficiency causes mitotic errors, neurogenesis defects, and brain dysfunction by disrupting microtubule dynamics and associated proteins.