Author

Pierre Lau

Italian Institute of TechnologyORCID 0000-0002-7367-364XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Devid DamianiiD· 2 shared Federico AnsaloniiD· 2 shared Luca PandolfiniiD· 2 shared Remo SangesiD· 2 shared Stefano GustincichiD· 2 shared A. Elizabeth de GuzmaniD· 1 shared Abraham Tettey‐MateyiD· 1 shared Alberto GalbuseraiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMolecular Biology

Devid DamianiORCID

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Author profile →

3 papers

Recent·Most cited

Sex-biasing influence of autism-associated Ube3a gene overdosage at connectomic, behavioral and transcriptomic levels

Caterina Montani, Luigi Balasco, Marco Pagani, Filomena Grazia Alvino, Noemi Barsotti, A. Elizabeth de Guzman, Alberto Galbusera, Alessia De Felice, Thomas Nickl‐Jockschat, Sara Migliarini, Simona Casarosa, Pierre Lau, Lorenzo Mattioni, Massimo Pasqualetti, Giovanni Provenzano, , Alessandro Gozzi

This study shows that Ube3a gene overdosage causes sex-biased effects on brain connectivity, behavior, and gene expression in mice, linking it to autism-related phenotypes.

Science Advances · Jul 12, 2024Peer-reviewedNeuroscience

Internal Ribosome Entry Sites act as Effector Domain in linear and circular antisense long non-coding SINEUP RNAs

Sabrina D’Agostino, Abraham Tettey‐Matey, Massimiliano Volpe, Bianca Pierattini, Federico Ansaloni, Pierre Lau, Carlotta Bon, Omar Peruzzo, Clarissa Braccia, Andrea Armirotti, Margherita Scarpato, Devid Damiani, Valerio Di Carlo, Laura Broglia, Elías Bechara, , Stefano Gustincich

This study identifies SINEUP RNAs with Internal Ribosomal Entry Site (IRES) sequences as effector domains, enhancing translation of target mRNAs through both linear and circular transcripts.

bioRxiv · May 25, 2023 · PreprintMolecular Biology

Pgbd5 impacts neuronal differentiation and double strand breaks signaling in the developing cortex

Alessandro Simi, Federico Ansaloni, Luca Spagnoletti, Damiano Mangoni, Pierre Lau, Diego Vozzi, Luca Pandolfini, Devid Damiani, Remo Sanges, Stefano Gustincich

This study shows Pgbd5 is essential for neuronal differentiation and radial migration in mouse corticogenesis, with effects on DNA double-strand breaks and gene expression.

bioRxiv · May 9, 2023 · PreprintDevelopmental Biology