Author
Children's Medical CenterORCID 0000-0003-2984-666XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Kalil G. Abdullah, Kenji Miki, Charles K. Edgar…·Samuel K. McBrayer
This study identifies GAA accumulation in gliomas as a driver of neuronal activity and tumor growth, linking cancer metabolism to neuroscience through GABAA receptor activation.
Alex C. Sternisha, Haocheng Li, Kumar Gajendra…·Samuel K. McBrayer
The paper develops a biosensor to monitor α-ketoglutarate in human cells and identifies a mitochondrial-to-nuclear pathway regulating chromatin methylation.
Yi Xiao, Diana D. Shi, Lei Guo…·Samuel K. McBrayer
This study shows mutant IDH reprograms neural progenitor cell fate by silencing Gsx2, promoting gliomagenesis through lineage switching.
Kailong Li, Yuxuan Liu, Hui Cao…·Jian Xu
This paper introduces enhanced CRISPR epigenetic editing systems to analyze enhancer function in vivo, showing improved modulation of gene transcription with minimal off-target effects.