Author

Julia N. Danon

Children's Hospital of PhiladelphiaORCID 0000-0001-6971-6582Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Nikolaos G. SgourakisiD· 2 shared Apala ChaudhuriiD· 1 shared Chloe Wang· 1 shared Daniel H. HwangiD· 1 shared Kimia Dasteh GoliiD· 1 shared Leena MallikiD· 1 shared Omkar Shinde· 1 shared Photis RotsidesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Nikolaos G. SgourakisORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 15, 2026

A miniaturized MR1 metabolite display system with native-like protein features

Photis Rotsides, Omkar Shinde, Julia N. Danon, Nikolaos G. Sgourakis

This paper develops a stabilized MR1 variant, SMART-MR1, that preserves native-like ligand presentation and TCR recognition while enabling biochemical and structural studies.

DOI 10.64898/2026.04.13.718121

structural biologyexperimental assay

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ImmunologyProceedings of the National Academy of SciencesPeer-reviewedJan 9, 2025

CryoEM structure of an MHC-I/TAPBPR peptide bound intermediate reveals the mechanism of antigen proofreading

Yi Sun, Ruth A. Pumroy, Leena Mallik…·Nikolaos G. Sgourakis

The paper determines the cryo-EM structure of an MHC-I/TAPBPR peptide intermediate, revealing how antigen proofreading occurs through transient peptide interactions.

10 citations

humancryo-EM

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