Yuan Jiang

The paper identifies a novel Cas12a variant, BvCas12a, with high specificity and engineers variants with broader PAM compatibility and improved editing efficiency.

This study benchmarks five cell-type-specific spatially variable gene detection methods using a simulation framework, revealing performance issues in realistic settings and providing a user guide for method selection.

This study identifies gut microbiota-mediated metabolites that influence intestinal helminth infection in zebrafish, highlighting potential therapeutic targets.