Yajun Xie

The paper identifies distinct progenitor populations in human ganglionic eminences, their gene regulatory networks, and lineage trajectories using single-nucleus transcriptomics and spatial transcriptomics.

The paper identifies 22 molecularly distinct neuronal subtypes in the lateral septum by profiling transcriptional identity and examines their connectivity, morphology, and electrophysiology.

The paper shows that intrinsic developmental origins and local signals shape septal astrocyte identity through distinct molecular and morphological features in medial and lateral septal nuclei.

This study shows that Sonic hedgehog signaling from cortical neurons regulates astrocyte development and synaptic connectivity during cortical circuit formation.

This study shows that Sonic hedgehog signaling in astrocytes is required for cell-type-specific synaptic organization and remodeling in the cortex.