Ya Jiang

This study constructs a transcriptional and epigenetic atlas of T cell development in neonatal and adult mice, identifying age-related gene regulatory programs and a conserved regulator, Zbtb20.

The paper identifies gene regulatory programs distinguishing naive CD8+ T cell subsets using RNA-seq and ATAC-seq data, revealing novel regulators and transcriptional networks.

This paper introduces CARP, a method combining RNA-seq and PRO-seq to distinguish direct miRNA targets from downstream regulatory changes, showing improved accuracy and reduced false positives.