Adrian J. McNairn

BLink-seq is a scalable Haplotagging method for generating phased haplotypes and detecting structural variants in non-model species using short-read sequencing.

The paper analyzes replicate flower color hybrid zones in Antirrhinum to identify loci associated with gene flow barriers using haplotagging, FST scans, and genealogical methods.

This study uses single-nucleus multi-omics to analyze fibrolamellar carcinoma, revealing rewired cell communication and potential therapeutic targets.

The paper identifies gene regulatory programs distinguishing naive CD8+ T cell subsets using RNA-seq and ATAC-seq data, revealing novel regulators and transcriptional networks.

This study identifies miR-375 as a key regulator of intestinal crypt homeostasis, showing its role in stem cell proliferation, tuft cell abundance, and resistance to infection and cancer.

The paper shows female mouse embryos are more susceptible to embryonic lethality from genomic instability-induced inflammation, which is mitigated by testosterone or anti-inflammatory drugs.

This study shows that MCMDC2 is essential for meiotic DNA break repair and homolog pairing in mice, with phenotypes similar to MSH4/5 deficiency.