Radiation therapy synergizes with mRNA vaccination to overcome microglia-mediated suppression of dendritic cell migration and T cell priming in glioblastoma
Amy J. Wisdom, Zachary J. Rogers, Fiona Chatterjee…·Stefani Spranger
Author
Koch Institute for Integrative Cancer Research At MITORCID 0000-0003-3014-813XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Amy J. Wisdom, Zachary J. Rogers, Fiona Chatterjee…·Stefani Spranger
Ryuhjin Ahn, Alicia D. D’Souza, Lawrence Long…·Forest M. White
The paper introduces INSIGHT, a platform for phosphoproteomic analysis of rare cell subpopulations, and applies it to study signaling changes in disseminated glioblastoma cells in vivo.
Mirae Kim, Ruth Dannenfelser, Yufei Cui…·Vicky Yao
The paper introduces an ontology-aware classification framework for DNA methylation data using a curated atlas of healthy human tissues and cell types, identifying CpG sites that accurately classify tissues and cell types.
Yufei Cui, Kien Phuong, Heidi M. Temple…·Forest M. White
The paper identifies cross-presented tumor antigens in glioblastoma and shows that targeting these antigens with mRNA vaccines improves anti-tumor immunity.
Tigist Y. Tamir, Shreya Chaudhary, Annie X Li…·Forest M. White
This study identifies sex-specific metabolic reprogramming in obesity by analyzing phosphorylation sites on metabolic enzymes and their functional impact.