Author

Zachary J. Rogers

Koch Institute for Integrative Cancer Research At MITORCID 0000-0002-4422-7907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

John Christopher LoveiD· 4 shared Stefani SprangeriD· 4 shared Fiona ChatterjeeiD· 3 shared Taylor A. HeimiD· 3 shared Vidit BhandarkariD· 3 shared Teresa DinteriD· 2 shared Tyler JacksiD· 2 shared Adam G. BergeriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersImmunology

John Christopher LoveORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Radiation therapy synergizes with mRNA vaccination to overcome microglia-mediated suppression of dendritic cell migration and T cell priming in glioblastoma

Amy J. Wisdom, Zachary J. Rogers, Fiona Chatterjee, Yufei Cui, Lizmarie Garcia-Rivera, Heidi M. Temple, Nouran S. Abdelfattah, Tobias Coombs, Richard Van, Cassandra Tafuri Del Vecchio, Hin Ka So, Taylor A. Heim, Grace Wolczanski, Christopher Mount, Vincent L. Butty, , Stefani Spranger

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Modeling lung adenocarcinoma using layer-by-layer nanoparticles mitigates innate immune cell activation

Vidit Bhandarkar, Elen Torres-Mejia, Taylor A. Heim, Namita Nabar, Tamara G. Dacoba, Zachary J. Rogers, Nicolas Mathey‐Andrews, Sean-Luc Shanahan, Chau Vo, Adam G. Berger, John Christopher Love, Tyler Jacks, Paula Therese Hammond, Stefani Spranger

This paper develops a nanoparticle-based method to deliver Cre mRNA for lung adenocarcinoma modeling in mice, avoiding immune activation and enabling accurate tumor-immune dynamics studies.

bioRxiv · Sep 20, 2026 · PreprintImmunology

Lymph node resident memory T cells retain effector capabilities by evading lung resident memory dysfunction.

Taylor A. Heim, Zachary J. Rogers, Sarah Marie Duquette, Molly Carney, Vidit Bhandarkar, Fiona Chatterjee, Teresa Dinter, Jason M. Schenkel, Scott R. Manalis, John Christopher Love, Stefani Spranger

This study identifies lymph node resident memory T cells (LNRM) as a distinct subset with unique effector capabilities compared to lung resident memory T cells and central memory T cells.

bioRxiv · Feb 5, 2026 · PreprintImmunology

PD-1 blockade during T cell priming enhances long-term protection against metastatic tumors by epigenetically tuning T cell exhaustion

Teresa Dinter, Sebastian D. Mackowiak, Zachary J. Rogers, Vidit Bhandarkar, Molly Y. Carney, Yiming J. Zhang, Duncan M. Morgan, Lorelai Pop, Fiona Chatterjee, Emi A. Lutz, Jain Yajit, Adityanarayanan Radhakrishnan, Eric S. Lander, Karl Dane Wittrup, John Christopher Love, , Stefani Spranger

This study shows PD-1 blockade during T cell priming promotes an intermediate-exhausted CD8 T cell state that supports durable anti-tumor immunity after surgery and metastatic challenge, better than effector or memory-like T cells.

bioRxiv · Nov 25, 2025 · PreprintImmunology