Author

Amy J. Wisdom

Harvard UniversityORCID 0000-0002-6098-5353Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Forest M. WhiteiD· 2 shared Heidi M. TempleiD· 2 shared Nouran S. AbdelfattahiD· 2 shared Stefani SprangeriD· 2 shared Yufei CuiiD· 2 shared Aastha SobtiiD· 1 shared Alex M. BassiliD· 1 shared Cassandra Tafuri Del Vecchio· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Forest M. WhiteORCID

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3 papers

Recent·Most cited

Radiation therapy synergizes with mRNA vaccination to overcome microglia-mediated suppression of dendritic cell migration and T cell priming in glioblastoma

Amy J. Wisdom, Zachary J. Rogers, Fiona Chatterjee, Yufei Cui, Lizmarie Garcia-Rivera, Heidi M. Temple, Nouran S. Abdelfattah, Tobias Coombs, Richard Van, Cassandra Tafuri Del Vecchio, Hin Ka So, Taylor A. Heim, Grace Wolczanski, Christopher Mount, Vincent L. Butty, , Stefani Spranger

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Analysis of tumor-derived and cross-presented peptide antigens defines improved immunotherapeutic strategies

Yufei Cui, Kien Phuong, Heidi M. Temple, Amy J. Wisdom, Nouran S. Abdelfattah, Stefani Spranger, Forest M. White

The paper identifies cross-presented tumor antigens in glioblastoma and shows that targeting these antigens with mRNA vaccines improves anti-tumor immunity.

bioRxiv · Feb 27, 2026 · PreprintImmunology

Differential Impact of Lymphocytes on Radiation Response in Autochthonous versus Transplant Sarcomas in Syngeneic Mice

Yvonne Marie Mowery, Aastha Sobti, Alex M. Bassil, Amy J. Wisdom, Collin L. Kent, Chang Su, Jonathon E. Himes, Eric S. Xu, Nerissa T. Williams, Lixia Luo, David G. Kirsch

The paper compares radiation response in autochthonous and transplant sarcomas in mice with and without adaptive immunity, finding higher cure rates in transplant tumors with immune function.

bioRxiv · Oct 5, 2025 · PreprintCancer Biology