Radiation therapy synergizes with mRNA vaccination to overcome microglia-mediated suppression of dendritic cell migration and T cell priming in glioblastoma
Amy J. Wisdom, Zachary J. Rogers, Fiona Chatterjee…·Stefani Spranger
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Massachusetts Institute of TechnologyORCID 0000-0002-2511-9353Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Amy J. Wisdom, Zachary J. Rogers, Fiona Chatterjee…·Stefani Spranger
Taylor A. Heim, Zachary J. Rogers, Sarah Marie Duquette…·Stefani Spranger
This study identifies lymph node resident memory T cells (LNRM) as a distinct subset with unique effector capabilities compared to lung resident memory T cells and central memory T cells.
Teresa Dinter, Sebastian D. Mackowiak, Zachary J. Rogers…·Stefani Spranger
This study shows PD-1 blockade during T cell priming promotes an intermediate-exhausted CD8 T cell state that supports durable anti-tumor immunity after surgery and metastatic challenge, better than effector or memory-like T cells.
Kevin Boardman, Siheng Xiang, Fiona Chatterjee…·Douglas E. Koshland
The paper identifies an interface between Scc2p and Smc1p that regulates cohesin ATPase activity and shows how acetylation of Smc3p inhibits this activity.
Vincent Guacci, Fiona Chatterjee, Brett Robison, Douglas E. Koshland
The paper shows that a cohesin subunit interface regulates DNA entrapment independently of a gate mechanism in yeast.