Huili Zheng

This study shows mammalian sperm use cytoplasmic droplets and mitochondria for protein synthesis during epididymal maturation, overcoming transcriptional silence to achieve motility and fertility.

This study shows that paternal metabolic recovery before conception remodels sperm RNA and reduces transmission of HFD-associated metabolic risk to offspring in mice.

This study shows that the X-linked miR-506 family miRNAs enhance sperm competitiveness and male reproductive fitness by fine-tuning gene expression during spermatogenesis.

This study shows that miR-465 cluster ablation causes female conceptus degeneration and a male-biased sex ratio in mice, indicating a sexual dimorphism in placental development.

The paper investigates the role of DNMT2 in maternal transmission of a paramutant phenotype through the male germline.

This study compares operant learning and memory between mice born via ICSI and naturally-conceived controls, finding sex-specific deficits in ICSI mice.

This study demonstrates that CRISPR-Mb3Cas12a can efficiently edit the mouse genome with minimal off-target effects and without requiring the TTTV PAM sequence.

The paper identifies artificial junction sequences formed by reverse transcriptases, leading to false circular RNA identification, and proposes methods to distinguish true circular RNAs.