Author

Joel L. Sax

Case Western Reserve UniversityORCID 0000-0003-3040-1836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

Bashar AmeriD· 1 shared Chaitan KhoslaiD· 1 shared Dharmaraja AllimuthuiD· 1 shared Drew AdamsiD· 1 shared Edward E. K. BaidooiD· 1 shared H. Dong· 1 shared Ilya R. BedermaniD· 1 shared Matthew S. ElittiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

Bashar AmerORCID

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2 papers

Recent·Most cited

NeuroscienceACS Chemical BiologyPeer-reviewedJul 14, 2022

Enhancers of human and rodent oligodendrocyte formation predominantly induce cholesterol precursor accumulation

Joel L. Sax, Samantha N. Hershman, Zita M L Hubler…·Drew Adams

This study identifies that many molecules promoting oligodendrocyte formation inhibit cholesterol pathway enzymes, with a focus on EBP, and proposes a model for their mechanism.

15 citations

humanmouse

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Synthetic BiologybioRxivPreprintAug 9, 2021

Engineering site-selective incorporation of fluorine into natural product analogs

Sasilada Sirirungruang, Omer Ad, Thomas M. Privalsky…·Michelle C. Y. Chang

This paper describes engineering a fluorine-selective enzyme to produce fluorinated polyketide analogs using E. coli.

DOI 10.1101/2021.08.09.455754

E. coliexperimental assay

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