Dharmaraja Allimuthu

This study shows that activating Gq-signaling in islet macrophages impairs β-cell insulin secretion via the AMPK-sphingolipid axis, revealing a new immune-endocrine communication mechanism.

The paper identifies small molecules that promote lipid droplet accumulation, which induces lysophagy and inhibits cancer cell proliferation.

This paper develops a mouse model of Parkinson's disease by overexpressing α-synuclein and demonstrates neuroprotection with PD180970.

This study identifies that many molecules promoting oligodendrocyte formation inhibit cholesterol pathway enzymes, with a focus on EBP, and proposes a model for their mechanism.