Catherine Werts

This study shows that archaeal cell envelopes activate innate immunity via TLR2, unlike bacteria which use multiple PRRs.

This study shows beta-lactam antibiotics induce a Jarisch-Herxheimer reaction in leptospirosis through TLR2/4 and TLR2/5-dependent mechanisms in mice and humans.

This study shows primary human dermal fibroblasts selectively respond to microbial ligands by secreting chemokines but not cytokines, indicating a specialized role in early immune surveillance.

This study shows that NOD2 stimulation with MDP reduces Cryptosporidium parvum infection in neonatal mice by increasing antimicrobial peptides and epithelial cell renewal.

This study identifies myocarditis and neutrophil-mediated vascular leakage as key factors in fatal murine leptospirosis, distinct from cytokine storm or organ failure.