Roland Wedlich‐Söldner

Molecular orchestration of global actin remodelling by INF2

This study identifies two mechanisms controlling INF2 activity, showing how they limit actin remodeling and impact cellular processes and disease.

The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility

The paper identifies Ldm1 and Ldo16 as actin-dependent lipid droplet motility mediators in yeast, showing their roles in LD movement and mitochondrial transport.

A Red Fluorescent Lifeact Marker to Study Actin Morphology in Podocytes

The paper introduces a red fluorescent Lifeact marker to study actin morphology in podocytes using intravital imaging and super-resolution microscopy.

Structure of the F-tractin-F-actin complex

The paper determines the structure of the F-tractin-F-actin complex using cryo-EM, revealing how F-tractin binds actin and induces bundling.

Pervasive head-to-tail insertions of DNA templates mask desired CRISPR/Cas9-mediated genome editing events

The paper identifies head-to-tail DNA template insertions in CRISPR/Cas9 editing and highlights the failure of PCR to detect them, advocating for comprehensive analysis.