Shaolei Xiong

This study identifies PDGFRβ+ pericytes as developmental brown adipocyte progenitors and shows that inhibiting the Notch/PDGFRβ axis promotes brown adipogenesis and improves metabolic health.

This study uses metabolomics to compare long- and short-term fasting responses in cave-dwelling and surface-dwelling Mexican tetra, identifying metabolic differences linked to resilience and longevity.

The paper identifies cis-regulatory changes in cavefish that contribute to metabolic adaptation by analyzing epigenetic differences between surface and cave populations.