Alexander Kenzior

Cave Adaptation Favors Aging Resilience in the Mexican Tetra

The paper compares aging markers between surface and cavefish populations of Astyanax mexicanus, finding that cavefish show less pronounced aging signatures and suggest metabolic shifts, particularly mitochondrial function, contribute to their extended longevity.

A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms

This study characterizes the CRY1 R263Q mutation in subterranean animals, showing altered circadian rhythms and gene expression in mice, but no major metabolic defects.

A chromosome level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution.

The paper presents a chromosome-level genome of surface fish Astyanax mexicanus and uses it to identify genetic factors contributing to trait evolution in cavefish populations.

Genome-wide analysis of cis-regulatory changes in the metabolic adaptation of cavefish

The paper identifies cis-regulatory changes in cavefish that contribute to metabolic adaptation by analyzing epigenetic differences between surface and cave populations.

Stable transgenesis in Astyanax mexicanus using the Tol2 transposase system.

The paper demonstrates the successful generation of stable transgenic lines in Astyanax mexicanus using the Tol2 transposase system, enabling the expression of fluorescent markers in specific cell types.