Jack M. Moen

This study investigates how RNA editing in cephalopods alters protein function through proteomics and biochemical assays, revealing its impact on protein stability, localization, and interactions.

This study identifies and corrects fitness defects in genomically recoded E. coli, improving growth and functional capabilities.

The paper systematically optimizes an orthogonal translation system to enhance its biological tolerance by minimizing host interactions and stress responses.

The paper systematically analyzes proteomic and genomic data of SARS-CoV-2 variants to identify how mutations affect viral gene expression, host interactions, and immune evasion.

The paper develops a platform to profile interactions between intracellular pathogens and the human phosphoproteome, identifying host-pathogen interactomes and expanding knowledge of viral protein function.