Author

Einar Kleinhans Krogsaeter

Gladstone InstitutesORCID 0000-0001-8232-5498Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Danielle L. SwaneyiD· 3 shared Erica J. StevensoniD· 3 shared Nevan J. KroganiD· 3 shared Alicia RichardsiD· 2 shared Justin McKetneyiD· 2 shared Yadong HuangiD· 2 shared Alexandra Willis· 1 shared Angelica Marquez· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersNeuroscience

Danielle L. SwaneyORCID

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Author profile →

3 papers

Recent·Most cited

APOE4 disrupts the central dogma by arresting neuronal proteome dynamics

Einar Kleinhans Krogsaeter, Justin McKetney, Lishi Li, Isabelle Liu, Alicia Richards, Vishvak Subramanyam, Keyi Yin, Martin Gordon, Pedro Belio Mairal, Erica J. Stevenson, Houzhen Qian, Yadong Huang, Hani Goodarzi, Nevan J. Krogan, Danielle L. Swaney

This study shows APOE4 disrupts neuronal proteome dynamics by impairing proteostasis, leading to protein accumulation and cellular stress before Alzheimer's disease onset.

bioRxiv · Jul 22, 2026 · PreprintNeuroscience

Functional diversification of the cephalopod proteome by RNA-editing

Jack M. Moen, Alicia Richards, Einar Kleinhans Krogsaeter, Benjamin J. Polacco, Martin E. Gordon, Erica J. Stevenson, Rhiana Boyles, Maximilien Burq, Dejan Štepec, Bryan Crampton, Peter Cimermančič, Joshua J. C. Rosenthal, Nevan J. Krogan, Danielle L. Swaney

This study investigates how RNA editing in cephalopods alters protein function through proteomics and biochemical assays, revealing its impact on protein stability, localization, and interactions.

bioRxiv · Dec 16, 2025 · PreprintMolecular Biology

Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction

Einar Kleinhans Krogsaeter, Justin McKetney, Leopoldo Valiente‐Banuet, Angelica Marquez, Alexandra Willis, Zeynep Cakir, Erica J. Stevenson, Gwendolyn Μ. Jang, Antara T. Rao, Emmy Li, Anton Zhou, Anjani Attili, Timothy S. Chang, Martin Kampmann, Yadong Huang, , Danielle L. Swaney

This study identifies lysosomal proteome changes caused by apoE4, linking them to lysosomal dysfunction and Alzheimer's disease pathology.

Autophagy · Oct 17, 2025Peer-reviewedNeuroscience