Author

Jan M. Bruder

Max Planck Institute for Molecular BiomedicineORCID 0000-0003-3126-0625Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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Christian FufezaniD· 1 shared Claudine KraftiD· 1 shared Cristián Eggers· 1 shared Fabienne Mollet· 1 shared Hannes C. A. DrexleriD· 1 shared Hans Robert SchöleriD· 1 shared Héctor MancillaiD· 1 shared Jie WuiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Christian FufezanORCID

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1 paper

Recent·Most cited

BiochemistryNucleic Acids ResearchPeer-reviewedNov 5, 2025

tRNA modifications tune decoding of codon pairs to prevent cellular quality control responses

Jie Wu, Cristián Eggers, Olga Sin…·Sebastian A. Leidel

This study shows that tRNA modifications affect codon pair decoding, leading to ribosome stalling and triggering quality control responses to prevent protein aggregation.

10 citations

proteomicsexperimental assay

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