Claudine Kraft

Modular assembly of mitochondrial complex III from a dynamic matrix domain pool

This study reveals how mitochondrial complex III assembles from preformed matrix domain modules, showing dynamic subunit exchange and the role of specific residues in assembly and disease.

The compartmentalized activity of a legume subtilase SBT12a allows symbiosome stabilization

This study identifies SBT12a as a subtilase that regulates symbiosome stability in legumes by degrading defense proteins and promoting symbiosis.

In situ visualization of autophagy suggests vesicle fusion can contribute to phagophore expansion

This study uses cryo-electron tomography to show that vesicle fusion contributes to phagophore expansion in yeast during autophagosome biogenesis.

Biomolecular condensate architecture of an autophagic cargo at molecular resolution in situ

The paper determines the molecular structure of autophagic cargo condensates using cryo-electron tomography and shows how disordered regions influence condensate properties.

tRNA modifications tune decoding of codon pairs to prevent cellular quality control responses

This study shows that tRNA modifications affect codon pair decoding, leading to ribosome stalling and triggering quality control responses to prevent protein aggregation.