Aino I. Järvelin

ADAR1 regulates alternative splicing through an RNA editing-independent mechanism.

This study shows ADAR1 regulates alternative splicing through both RNA editing-dependent and editing-independent mechanisms, with the latter having greater impact.

Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection

This study identifies 104 cellular RNA-binding proteins within HIV-1 particles, revealing their role in viral gene expression and infectivity through interactions with HIV-1 genomic RNA.

Syncrip/hnRNPQ is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation

This study identifies Syncrip/hnRNPQ as a regulator of activity-induced Msp300/Nesprin-1 expression and new synapse formation through local translation.

Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability

The paper shows that Imp/IGF2BP regulates neural stem cell growth and division in Drosophila by stabilizing myc mRNA, affecting cell size and division rates.

Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

The paper shows that larval neurons upregulate Prospero protein through alternative polyadenylation and Syncrip-mediated mRNA stabilization.

Understanding RNP remodelling uncovers RBPs functionally required for viral replication

The paper investigates how RNA-binding proteins (RBPs) change in response to viral infection and identifies RBPs crucial for viral replication.