Author

Christina N. Vallianatos

University of MichiganORCID 0000-0003-3159-3200Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Patricia Marie GarayiD· 2 shared Robert S. PorteriD· 2 shared Shigeki IwaseiD· 2 shared Brynne RainesiD· 1 shared Catherine E. KeeganiD· 1 shared Emily T. MaclaryiD· 1 shared Katherine M. BonefasiD· 1 shared Katie M. Collette· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetics

Patricia Marie GarayORCID

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2 papers

Recent·Most cited

Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation

Christina N. Vallianatos, Brynne Raines, Robert S. Porter, Katherine M. Bonefas, Michael C. Wu, Patricia Marie Garay, Katie M. Collette, Young Ah Seo, Yali Dou, Catherine E. Keegan, Natalie Celia Tronson, Shigeki Iwase

This study shows that KMT2A and KDM5C, which have opposing enzymatic activities, work together to regulate neuronal structure, behavior, and H3K4 methylation, with their combined loss reversing some phenotypes.

Communications Biology · Jun 1, 2020Peer-reviewedGenetics

Induction of X-chromosome Inactivation by the Histone Demethylase SMCX/KDM5C

Srimonta Gayen, Emily T. Maclary, Yumie Murata-Nakamura, Christina N. Vallianatos, Robert S. Porter, Patricia Marie Garay, Shigeki Iwase, Sundeep Kalantry

This study shows that SMCX/KDM5C, a histone demethylase, is required for X-inactivation in female mammals by inducing Xist RNA and silencing X-linked genes.

bioRxiv · Aug 11, 2017 · PreprintGenetics