Megan E. Fox

The paper examines molecular adaptations in VTA neurons during fentanyl withdrawal, finding distinct transcriptional responses based on projection targets.

This study investigates how VTA-NAc and VTA-PFC circuits contribute to fentanyl-context associations and identifies distinct dopamine receptor roles in context-seeking behavior.

The paper identifies female-specific transcriptional changes in nucleus accumbens neuron subtypes under chronic social stress and highlights PI3K-Akt-mTOR signaling as a conserved pathway.

This study investigates fentanyl relapse mechanisms using a Drd1-cre mouse line, finding blunted fentanyl seeking despite similar self-administration and increased D1 receptor expression.

This study identifies transcriptional changes in mouse VTA cell types after fentanyl self-administration using single nuclei RNA sequencing.

This study examines transcriptomic changes in reward and sensory brain regions of juvenile mice exposed to perinatal fentanyl, revealing sex-specific gene expression patterns and enriched biological processes.

The paper characterizes VP Npas1+ neurons' projections, molecular identity, and role in stress response through RNA-seq and chemogenetic manipulation.

This study identifies Nr4a1's role in cocaine reward by analyzing VP gene expression and manipulating Nr4a1 in specific neurons.

This study identifies molecular and structural changes in nucleus accumbens neuron subtypes during fentanyl abstinence that mediate negative emotional behaviors.

This study shows chronic psychosocial stress increases fentanyl consumption in male but not female C57BL/6 mice, with changes in nucleus accumbens Rho GTPases expression.

This study shows that perinatal fentanyl exposure causes long-term impairments in somatosensory function and behavior in mice, with changes in synaptic and morphological properties.

This study compares fentanyl withdrawal and associated pain in mice and rats, finding species-specific differences in withdrawal symptoms and pain expression.

The paper investigates how TrkB deletion in D1-MSNs leads to stereotypy behavior and identifies molecular and morphological changes in these neurons.

This study shows that perinatal fentanyl exposure in mice leads to somatic withdrawal and lifelong neurobehavioral changes similar to human neonatal opioid withdrawal syndrome.