Author

Martin Hruska

West Virginia UniversityORCID 0000-0003-3186-770XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:imaging· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adam Skeens· 1 shared Adema RibiciD· 1 shared Andranik Avedisyan· 1 shared Ariel A. Jacobi· 1 shared Chao-Yin CheniD· 1 shared Delaney G EavesiD· 1 shared Grace C. Jones· 1 shared James D. ScripteriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperNeuroscience

Adam Skeens

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Robust learning-driven structural and functional plasticity of spines in the mature mouse cortex

Mona Fariborzi, Delaney G Eaves, Lara Y. Demir, Yuxi Wu, Adam Skeens, Martin Hruska, Adema Ribic

This study shows that learning increases spine complexity and formation in adult mice, while reducing spine size, and that spine response discriminability predicts learning performance.

bioRxiv · Jun 9, 2026 · PreprintNeuroscience

A Unifying Mechanism for Synaptic Amyloid beta Toxicity Beta Adrenergic Potentiation of the Ca2+ Channel CaV1.2 by Amyloid beta

Peter H. Bartels, Sarah L. S. Rougé, James D. Scripter, Zhuoer Zeng, Zoila M. Estrada‐Tobar, Jennifer Price, Ariel A. Jacobi, Ruben A. Berumen, Sheng‐Yang Ho, Andranik Avedisyan, Yang K. Xiang, Chao-Yin Chen, Madeline Nieves‐Cintrón, Manuel F. Navedo, Mary C. Horne, , Johannes W. Hell

This paper identifies a mechanism by which amyloid beta potentiates CaV1.2 channels via β2AR, leading to synaptic dysfunction and neurotoxicity, and shows that disrupting this pathway prevents these effects.

bioRxiv · Apr 29, 2026 · PreprintNeuroscience

Nanoscale analysis of functionally diverse glutamatergic synapses in the neocortex reveals input and layer-specific organization

Grace C. Jones, Yeasmin Akter, Victoria Shifflett, Martin Hruska

The paper uses STED nanoscopy to analyze synaptic nanoarchitecture in neocortical synapses, revealing input and layer-specific organization.

bioRxiv · May 1, 2024 · PreprintNeuroscience