Erin K. O’Shea

Plasticity-induced actin polymerization positions endocytic compartments at the bases of stimulated spines

The paper shows that actin polymerization in dendritic shafts positions endocytic compartments at stimulated spine bases, enhancing glutamate receptor turnover and spine enlargement.

Activity-dependent synapse elimination requires caspase-3 activation

This study shows that caspase-3 activation is essential for activity-dependent synapse elimination during development and in Alzheimer's disease models.

Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking

The paper investigates how actin polymerization in dendritic shafts regulates the trafficking of AMPA receptor-containing vesicles during long-term potentiation.

The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease

Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria

The paper shows natural light changes affect circadian gene expression in cyanobacteria through RNA polymerase recruitment controlled by transcription factors.

Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian clock

This study shows that the cyanobacterial circadian clock, via RpaA, coordinates metabolic programs to maintain energy status and viability under light/dark cycles.