Synthetic BiologybioRxivPreprint
Translation in a Box: Orthogonal Evolution in the Saccharomyces cerevisiae Mitochondrion
Brooke Rothschild-Mancinelli, Claudia Álvarez-Carreño, Wenying Guo…·Loren Dean Williams
This paper demonstrates the directed evolution of the Saccharomyces cerevisiae mitochondrial translation system as an orthogonal system to the cytosolic TS, revealing functional dependencies and enabling translation engineering.
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