Scott S. Howard

This study shows chronic compression transforms macrophages into a pro-tumor state, resembling glioma-associated macrophages, independent of tumor cell factors.

This study uses instant FLIM to show that mechanical compression of stromal cells in breast cancer models alters their metabolism, with distinct effects on fibroblasts and adipocytes, validated by transcriptomics and mitochondrial analysis.

This paper introduces DenseED blocks to train super-resolution microscopy networks with small datasets, achieving higher PSNR and resolution than conventional models.

The paper develops a CNN-based denoising method for mixed Poisson-Gaussian noise in fluorescence microscopy images, achieving real-time performance and superior SNR improvement.

This paper introduces instant FLIM, a real-time fluorescence lifetime imaging method, and demonstrates its application in long-term in vivo brain imaging in zebrafish and mice.

This study shows YAP and TAZ redundantly promote bone development by regulating collagen I expression and organization through TEAD4 binding.