Author

MaKayla F. Cox

University of KentuckyORCID 0000-0002-7625-5339Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam D. BachstetteriD· 2 shared Kelly N. Roberts· 2 shared Leke Bytyqi· 2 shared Teresa Macheda· 2 shared Andrzej BartkeiD· 1 shared Bruce F. O’HaraiD· 1 shared Caleigh A. FindleyiD· 1 shared Carrie E. Johnson· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Adam D. BachstetterORCID

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3 papers

Recent·Most cited

Closed-head injury produces a delayed, region-specific defect in glucose-carbon routing at the pyruvate branchpoint in APP/PS1 KI mice

Elika Z. Moallem, Ronald C. Bruntz, MaKayla F. Cox, Leke Bytyqi, Taylor K Roberts, Samir P. Patel, Teresa Macheda, Kelly N. Roberts, Emma K. Higgins, Ramon C. Sun, Matthew S. Gentry, Patrick G. Sullivan, Lance A. Johnson, Adam D. Bachstetter

The paper investigates delayed glucose metabolism changes in APP/PS1 KI mice after closed-head injury, finding increased pyruvate and lactate labeling in cortex and hippocampus 8 months post-injury.

bioRxiv · Oct 6, 2026 · PreprintNeuroscience

Dim light at night impacts circadian rhythms and Alzheimer's disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in mice

Marilyn J. Duncan, Margaret R. Hawkins, Leke Bytyqi, Haleigh R Whitlock, Savannah M Shepard, MaKayla F. Cox, Esther G. Drinkard, Teresa Macheda, Kelly N. Roberts, Katharina Köhler, Mariella Schmidt, Carrie E. Johnson, Sridhar Sunderam, Bruce F. O’Hara, Michael Paul Murphy, Adam D. Bachstetter

This study shows that dim light at night disrupts circadian rhythms and increases amyloid pathology and microglial activation in a mouse model of Alzheimer's disease.

SLEEP · Feb 20, 2026Peer-reviewedNeuroscience

Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice

Samuel McFadden, Mackenzie R. Peck, Lindsey N. Sime, MaKayla F. Cox, Erol D. Ikiz, Caleigh A. Findley, Kathleen Quinn, Yimin Fang, Andrzej Bartke, Erin R. Hascup

This study shows that thermotherapy improves metabolism and cognition in male APP/PS1 mice but worsens spatial memory in female APP/PS1 mice.

Aging · Nov 29, 2024Peer-reviewedNeuroscience