Author

Elika Z. Moallem

University of KentuckyORCID 0009-0004-4271-4586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adam D. BachstetteriD· 3 shared Patrick G. SullivaniD· 3 shared Hemendra J. VekariaiD· 2 shared Kelly N. Roberts· 2 shared Samir P. PateliD· 2 shared Teresa Macheda· 2 shared Chirayu D. PandyaiD· 1 shared Emma K. Higgins· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Adam D. BachstetterORCID

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3 papers

Recent·Most cited

Closed-head injury produces a delayed, region-specific defect in glucose-carbon routing at the pyruvate branchpoint in APP/PS1 KI mice

Elika Z. Moallem, Ronald C. Bruntz, MaKayla F. Cox, Leke Bytyqi, Taylor K Roberts, Samir P. Patel, Teresa Macheda, Kelly N. Roberts, Emma K. Higgins, Ramon C. Sun, Matthew S. Gentry, Patrick G. Sullivan, Lance A. Johnson, Adam D. Bachstetter

The paper investigates delayed glucose metabolism changes in APP/PS1 KI mice after closed-head injury, finding increased pyruvate and lactate labeling in cortex and hippocampus 8 months post-injury.

bioRxiv · Oct 6, 2026 · PreprintNeuroscience

Spatial, temporal and sex specific mitochondrial dynamic changes in severe controlled cortical impact mouse model of traumatic brain injury

Hemendra J. Vekaria, Chirayu D. Pandya, Paresh Prajapati, Elika Z. Moallem, Gopal V. Velmurugan, W. Brad Hubbard, Adam D. Bachstetter, Patrick G. Sullivan

This study examines sex-specific mitochondrial changes in a mouse model of traumatic brain injury, revealing distinct spatial and temporal responses in mitochondrial function across brain regions.

bioRxiv · Apr 23, 2026 · PreprintNeuroscience

Traumatic brain injury exacerbates mitochondrial dysfunction in APP/PS1 knock-in mice through time-dependent pathways

Elika Z. Moallem, Hemendra J. Vekaria, Teresa Macheda, Margaret R. Hawkins, Kelly N. Roberts, Samir P. Patel, Patrick G. Sullivan, Adam D. Bachstetter

This study shows that traumatic brain injury worsens mitochondrial dysfunction in APP/PS1 mice through time-dependent mechanisms, with sex differences in vulnerability.

Experimental Neurology · Dec 30, 2025Peer-reviewedNeuroscience