Author

Rayne R. Lim

University of WashingtonORCID 0000-0003-3292-9204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

Jennifer R. ChaoiD· 2 shared Jianhai DuiD· 2 shared Mark EminhizeriD· 2 shared Sheldon Niernberger· 2 shared Abbi L. EngeliD· 1 shared Anju E. ThomasiD· 1 shared Aparna RamasubramanianiD· 1 shared Aspen Tong· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

Jennifer R. ChaoORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 7, 2026

Nutrient Microenvironments Reprogram Pigment Epithelium Metabolism and Phenotype

Rayne R. Lim, Emily Zhao, Daniel T. Hass…·Jennifer R. Chao

This study examines how different nutrient microenvironments affect RPE cell phenotype, function, and metabolism in iPSC and fetal RPE, identifying key metabolic shifts and phenotypic changes.

DOI 10.64898/2026.02.11.705448

humanbulk RNA-seq

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NeurosciencebioRxivPreprintOct 30, 2024

Retinal microglia-derived S100A9 incite NLRP3 inflammasome in a Western diet fed Ossabaw pig retina

Rayne R. Lim, Anju E. Thomas, Aparna Ramasubramanian, Shyam Sunder Chaurasia

This study shows that retinal microglia-derived S100A9 activates the NLRP3 inflammasome in Western diet-fed Ossabaw pigs, contributing to diabetic retinopathy.

4 citations

plant (other)bulk RNA-seq

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BiochemistryInvestigative Ophthalmology & Visual SciencePeer-reviewedSep 4, 2024

Metabolic phenotyping of healthy and diseased human RPE cells

Saira Rizwan, Beverly Toothman, Bo Li…·Jianhai Du

This study identifies nutrient utilization differences between healthy and diseased human RPE cells, showing reduced metabolic flexibility in SFD RPE and the impact of differentiation on nutrient use.

10 citations

humanmetabolomics

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