Author

Arigela Harikumar

University of MiamiORCID 0000-0003-3293-7618Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Felipe BeckedorffiD· 2 shared Helena Gomes Dos SantosiD· 2 shared Ramin ShiekhattariD· 2 shared Fan LiuiD· 1 shared Jingyin YueiD· 1 shared Justin M. WattsiD· 1 shared Mina Masoumeh TayariiD· 1 shared Monica Valencia· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Felipe BeckedorffORCID

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2 papers

Recent·Most cited

Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML

Mina Masoumeh Tayari, Helena Gomes Dos Santos, Sadat Dokaneheifard, Samuel D. Whedon, Monica Valencia, Arigela Harikumar, Felipe Beckedorff, Justin M. Watts, Philip A. Cole, Ramin Shiekhattar

The paper shows that Corin, a dual LSD1/CoREST inhibitor, synergizes with ATRA to induce differentiation and apoptosis in AML by disrupting CoREST-RAR/RXR complexes and recruiting p300.

bioRxiv · Oct 13, 2025 · PreprintMolecular Biology

Enhancing Transcriptome Mapping with Rapid PRO-seq Profiling of Nascent RNA

Pradeep Reddy Cingaram, Felipe Beckedorff, Jingyin Yue, Fan Liu, Helena Gomes Dos Santos, Arigela Harikumar, Ramin Shiekhattar

This paper introduces rPRO-seq, a rapid PRO-seq method for nascent RNA profiling, and applies it to study Integrator's role in mouse hematopoietic stem cell homeostasis.

Molecular Cell · Jul 24, 2025Peer-reviewedMolecular Biology