Arezoo M. Ardekani

This paper develops a multiscale computational framework to model PEGylated lipid nanoparticle transport through the extracellular matrix, showing that even low PEG density significantly enhances diffusivity.

This study investigates NP diffusion in HA solutions, finding anomalous diffusion dependent on particle size and HA mesh size, with implications for drug delivery.

The paper investigates RNA post hoc loading into empty lipid nanoparticles using turbulent mixing and finds it occurs within 12 ms under optimal conditions.

This paper develops a multiscale model to simulate peptide absorption after subcutaneous injection, showing how binding and oligomerization affect release and distribution.

This study investigates how arginine affects protein interfacial behavior, finding it weakens protein-protein interactions but with concentration and protein-specific variations.

This study models lipid nanoparticle transport through extracellular matrix, showing how particle size and rigidity affect diffusion and highlighting the importance of particle-to-matrix size ratio.

This study examines how mixing techniques and ethanol removal affect lipid nanoparticle (LNP) physicochemical properties using SAXS and computational fluid dynamics.

The paper compares the effects of eleven mixing techniques on mRNA lipid nanoparticle physicochemistry and biological performance, finding significant differences in particle properties and performance across methods.

The paper evaluates amplification lag in paper-based LAMP assays and shows BSA pre-coating reduces it by improving diffusion and reducing adsorption.

This paper develops a Raman spectroscopy tool for real-time monitoring of attenuated CMV in flow, demonstrating its ability to detect viral particles at high flow rates and across concentrations.

This study uses machine learning to classify chronic inflammatory diseases based on gut microbiota patterns and response to fiber, achieving up to 95% accuracy in distinguishing between conditions with overlapping dysbiosis.

This study determines the limit of detection of Raman spectroscopy for polystyrene particles in aqueous suspensions, showing its potential for detecting small particles like viruses.

This study compares the rheological and lipid properties of minipig and human skin across different anatomical locations and depths, revealing species, location, depth, and sex-based differences.