Author

Fabian Nikolka

Technische Universität Braunschweig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Karsten HilleriD· 2 shared A. N. FROLOViD· 1 shared Aistė Skorupskaitė· 1 shared Alexander VisekrunaiD· 1 shared Bastian Bennühr· 1 shared Christoph K. Stein‐ThoeringeriD· 1 shared Christoph ThieleiD· 1 shared Dirk Hans BuschiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Karsten HillerORCID

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2 papers

Recent·Most cited

Kupffer cells control neonatal hepatic metabolism via Igf1 signaling

Nikola Makdissi, DORIS J. HIRSCHMANN, A. N. FROLOV, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed H. Yaghmour, Philipp Arnold, Lorenzo Bonaguro, M Becker, Christoph Thiele, Felix Meissner, , Elvira Mass

This study shows that yolk sac-derived Kupffer cells regulate neonatal hepatocyte metabolism via Igf1 signaling, essential for glycogen storage and TCA cycle function.

Development · Dec 29, 2025Peer-reviewedDevelopmental Biology

Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells

Sarah Staudt, Fabian Nikolka, Markus Perl, Julia Franz, Noémie Leblay, Xiaoli-Kat Yuan, M. Larrayoz, Teresa Lozano, Linda Warmuth, Matthias A. Fante, Aistė Skorupskaitė, Teng Fei, Maria Bromberg, Patxi San Martín‐Úriz, Juan R. Rodríguez-Madoz, , Maik Luu

This study shows that pentanoate, a microbial postbiotic, is metabolized to citrate, which influences T cell differentiation and anti-cancer CAR T cell efficacy through epigenetic mechanisms.

bioRxiv · Aug 19, 2024 · PreprintImmunology