Author

Jessica Nouws

Yale UniversityORCID 0000-0003-3347-3595Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Maor SauleriD· 2 shared Charles S. Dela CruziD· 1 shared John E. McDonoughiD· 1 shared Juan IovannaiD· 1 shared Lokesh SharmaiD· 1 shared Pan ChaiD· 1 shared Patricia Santofimia‐CastañoiD· 1 shared R. Brewster· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Maor SaulerORCID

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2 papers

Recent·Most cited

BioinformaticsRespiratory ResearchPeer-reviewedDec 9, 2025

Integrative Single-Cell RNA and ATAC Sequencing Reveals the Impact of Chronic Cigarette Smoking on Lung Epithelial Responses to Influenza and Hyperoxia

Pan Cha, Zhenyang Zou, Jessica Nouws…·Maor Sauler

This study uses scRNA-seq and scATAC-seq to show chronic cigarette smoke exposure enhances inflammatory and survival pathways in lung epithelial responses to influenza and hyperoxia.

2 citations

mousescRNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintApr 27, 2025

The ferroptosis inhibitor NUPR1 coordinates the mitochondrial response to oxidative stress and cell metabolism during COPD pathogenesis in the lung

Saul S. Siller, Tao Yang, Jessica Nouws…·Maor Sauler

This study shows NUPR1 inhibition worsens oxidative stress, mitochondrial dysfunction, and metabolic imbalance in COPD, linking it to ferroptosis and disease progression.

DOI 10.1101/2025.04.27.650854

mousehuman

𝕏 PostBluesky