Author

Paulina Podszywalow‐Bartnicka

Instytut Biologii Doświadczalnej im. Marcelego NenckiegoORCID 0000-0002-4965-828XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Karla M. NeugebaueriD· 3 shared Bac Viet LeiD· 2 shared Katarzyna PiwockaiD· 2 shared Leonard SchärfeniD· 2 shared Tomasz SkórskiiD· 2 shared Agnieszka KępczyńskaiD· 1 shared Alfonso BellacosaiD· 1 shared Anna Mietelska‐PorowskaiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Karla M. NeugebauerORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TIAR-dependent coordination of alternative splicing and lipid peroxidation is required for CML cell resistance to imatinib in the bone marrow stroma

Paulina Podszywalow‐Bartnicka, Ewa Kozłowska, Remigiusz Adam Serwa, Joanna Idaszek, Ewa Walejewska, Agnieszka Kępczyńska, Anna Mietelska‐Porowska, Paulina Pilanc, Magdalena Wołczyk, Leonard Schärfen, Bac Viet Le, Wojciech Święszkowski, Katarzyna Piwocka, Tomasz Skórski, Karla M. Neugebauer

bioRxiv · Jul 15, 2026 · PreprintCancer Biology

Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib

Paulina Podszywalow‐Bartnicka, Morgan Shine, Jing Lin, Karla M. Neugebauer

The paper quantifies transcriptional readthrough in CML cells after imatinib treatment and shows it precedes alternative splicing changes and resistance development.

Science Advances · Mar 20, 2026Peer-reviewedMolecular Biology

Pol is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells

Bac Viet Le, Umeshkumar M. Vekariya, Monika Maria Toma, Margaret Nieborowska-Skorska, Marie‐Christine Caron, Malgorzata Gozdecka, Zayd Haydar, Martin Walsh, Jayashri Ghosh, Elaine Vaughan‐Williams, Paulina Podszywalow‐Bartnicka, Anna-Mariya Kukuyan, Sylwia Ziółkowska, Jessica Atkins, Emir Hadzijusufovic, , Tomasz Skórski

This study identifies Polθ as a therapeutic target in DNMT3A-mutated leukemia by showing its essential role in DNA repair and replication fork restart, and demonstrates that its inhibition enhances standard therapies.

Cell Reports Medicine · Mar 1, 2026Peer-reviewedCancer Biology

Control of gene output by intron RNA structure

Leonard Schärfen, Pernille Bech, Paulina Podszywalow‐Bartnicka, Karla M. Neugebauer

This study investigates how intron RNA structure affects gene expression using reporter assays and machine learning, finding that base pairing significantly modulates mRNA and protein levels.

bioRxiv · Nov 8, 2025 · PreprintBiochemistry