Author
Griffith UniversityORCID 0000-0003-3365-4679Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Yanyao Cai, J. LAZAR, Yun Shi…·Joseph P. Gerdt
The paper identifies chemical inhibitors of SpbK, an antiphage defense system in Bacillus subtilis, showing they promote phage dissemination and reveal mechanisms of inhibiting TIR-domain enzymes.
Biswa P. Mishra, Veronika Masic, Tamim Mosaiab…·Thomas Ve
This study shows that 3'cADPR-induced SIR2 filament formation activates ThsA effectors in type I Thoeris systems across bacterial species.
Zhiyu Zang, Olivia K. Duncan, Dziugas Sabonis…·Joseph P. Gerdt
This study identifies chemical inhibitors that block a bacterial immune system, enhancing phage therapy efficacy against resistant strains.
Yo Sasaki, Jian Zhu, Yun Yu Shi…·Jeffrey Milbrandt
The paper identifies nicotinic acid mononucleotide (NaMN) as an allosteric inhibitor of SARM1 that promotes axonal protection by blocking NMN binding and stabilizing the inactive SARM1 conformation.