Patricia Lorden

This study identifies MET signaling as a targetable vulnerability in rhabdoid tumors through integrated single-cell multi-omic and spatial transcriptomics analyses.

The paper uses spatial molecular imaging data to map human tonsil architecture and provides an analytical framework for Spatial Immunology.

The paper uses single-cell sequencing and spatial transcriptomics to compare immune responses in leptomeningeal disease with other CNS disorders, identifying disease-specific immune environments and progression mechanisms.

This study investigates X-chromosome inactivation and reactivation dynamics in female mouse PGCLCs, showing that a precise temporal sequence is critical for meiotic potential.

This study analyzes the transcriptomes of human oocytes at different maturation stages and finds that age affects specific gene pathways in matured oocytes.