Author

Alain Hovnanian

Hôpital Necker-Enfants MaladesORCID 0000-0003-3412-7512Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Johann Eli GudjonssoniD· 2 shared Lam C. TsoiiD· 2 shared Amanda OroscoiD· 1 shared Carole A. ParentiD· 1 shared Craig N. JohnsoniD· 1 shared Dajia WangiD· 1 shared Emilia Puig LombardiiD· 1 shared Erez CoheniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPathology

Johann Eli GudjonssonORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintJun 4, 2026

Multiomic Analysis Reveals an IFN-driven Cellular Landscape Effectively Targeted by Ruxolitinib in Hailey-Hailey Disease

Sara Ceccacci, Hoang Duc Minh Pham, Marion Dessaignes…·Alain Hovnanian

This study uses multiomic analysis to identify IFN signaling as a key driver in Hailey-Hailey disease and shows that ruxolitinib treatment reduces inflammation and improves patient outcomes.

DOI 10.64898/2026.06.01.729262

humanbulk RNA-seq

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ImmunologyScience Translational MedicinePeer-reviewedApr 8, 2026

Keratin 16 spatially inhibits type I interferon responses in stressed and diseased skin

Erez Cohen, Yang Xu, Sonal Ghodke…·Pierre A. Coulombe

This study shows KRT16 inhibits type I interferon signaling and innate immunity in skin diseases, providing new insights into inflammatory skin disorder mechanisms.

7 citationstop 1%

humanmouse

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