Author

Vivek S. Peche

St. Jude Children's Research HospitalORCID 0000-0003-3415-8765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adeleye Oluwatosin AdeshakiniD· 2 shared Stephen M GottschalkiD· 2 shared Andrew N. Nemecek· 1 shared Anthony A. HighiD· 1 shared Ben YoungbloodiD· 1 shared Brian CoventryiD· 1 shared Christopher C. DeRenzoiD· 1 shared David A. BakeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Adeleye Oluwatosin AdeshakinORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 22, 2026

Reprogramming CAR T-Cells with designed bioPROTACs

Vivek S. Peche, Sebastian Kenny, Tae Gun Kang…·Stephen M Gottschalk

This paper demonstrates that bioPROTACs can reprogram CAR T-cells by targeting DNMT3A, offering a tunable alternative to gene editing for enhancing T-cell function.

1 citation

humanexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 20, 2025

Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment

Adeleye Oluwatosin Adeshakin, Hao Shi, S. Scott Perry…·Stephen M Gottschalk

This study shows that deleting Regnase-1 in CAR T cells enhances their antitumor activity against osteosarcoma by creating a proinflammatory tumor microenvironment.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky