Menelaos Symeonides

This study identifies Lck and Fyn as essential Src family kinases required for T cell transendothelial migration through their regulation of PI3K signaling and cytoskeletal dynamics.

This study identifies BCR-dependent enhancement (BDE) as a mechanism by which DENV infects B cells, showing that BCR-E protein interactions and dynamin-mediated entry are critical for viral replication in these cells.

This study shows Vif regulates HIV-1-induced cell-cell fusion through Aurora kinase signaling, with Ezrin as a downstream effector.

This study identifies HIV-1-induced small T cell syncytia as a distinct infected subpopulation with increased susceptibility to NK cell killing.

This study identifies CasL as a regulator of T cell migration by controlling membrane blebbing during integrin-dependent movement into inflamed tissue.