Nathan H. Roy

This study identifies Lck and Fyn as essential Src family kinases required for T cell transendothelial migration through their regulation of PI3K signaling and cytoskeletal dynamics.

This study identifies a PIP5K-Ras bistable circuit that drives plasma membrane symmetry breaking, leading to cellular polarity and migration.

This study identifies CasL as a regulator of T cell migration by controlling membrane blebbing during integrin-dependent movement into inflamed tissue.

This study shows DENV structural proteins are surface-expressed on infected cells and can be targeted by antibodies for phagocytic clearance, bypassing ADE risks.

Rewritten Fiji plugin TrackMate now uses StarDist, ilastik, Weka, MorphoLibJ or imported label images as detectors, stores 2D object contours, and tracks shape and intensity over time.