Gilles Mithieux

This study investigates how food restriction in a mouse model of anorexia nervosa affects gut microbiota and intestinal gluconeogenesis, revealing their roles in maintaining glucose homeostasis.

This paper performs a meta-analysis of rodent studies to identify a common gut microbial signature associated with endocrine-disrupting chemicals-induced diabetes.

This study identifies adipocyte lipolysis as a critical metabolic process that prevents sepsis in mice by supporting energy metabolism and thermoregulation through insulin signaling, without affecting bacterial burden.

This study shows that reducing CAV1 in the liver decreases glucose production and improves metabolic parameters in diabetic mice.

This paper shows that GSD1a patient fibroblasts retain a reversible disease phenotype in vitro, driven by epigenetic and transcriptional changes, and that a drug can reverse these effects.