Author

Irem Uppman

Uppsala UniversityORCID 0000-0003-3602-5544Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Irem Uppman1 paper · Uppsala University

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Anders SundströmiD· 1 shared Cecilia C. KronaiD· 1 shared Faidra VoukelatouiD· 1 shared Francesco LatiniiD· 1 shared Fredrik J. SwartlingiD· 1 shared Hitesh Bhagavanbhai MangukiyaiD· 1 shared Ida LarssoniD· 1 shared Inês NevesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Anders SundströmORCID

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2 papers

Recent·Most cited

Identification of an epigenetically and phenotypically distinct peritumoral glioblastoma cell population linked to inferior patient outcome

Inês Neves, Xi Lü, Veera Jokinen, Francesco Latini, Nagaprathyusha Maturi, Anders Sundström, Yonglong Dang, Irem Yildirim, Tobias Bergström, Pengwei Xing, Mats Ryttlefors, Xingqi Chen, Fredrik J. Swartling, Lene Uhrbom

The paper identifies a distinct peritumoral glioblastoma cell population with unique epigenetic and phenotypic features associated with poor patient outcomes.

bioRxiv · Jan 17, 2026 · PreprintCancer Biology

The invasion phenotypes of glioblastoma depend on plastic and reprogrammable cell states

Milena Doroszko, Rebecka Stockgard, Irem Uppman, Josephine Heinold, Faidra Voukelatou, Hitesh Bhagavanbhai Mangukiya, Thomas O Millner, Madeleine Skeppås, Mar Ballester Bravo, Ramy Elgendy, Maria Berglund, Ludmila Elfineh, Cecilia C. Krona, Soumi Kundu, Katarzyna Koltowska, , Sven Nelander

This study identifies cell state-specific regulators of glioblastoma invasion routes using single-cell transcriptomics and spatial proteomics, showing their impact on patient survival and therapeutic potential.

Nature Communications · Jul 19, 2025Peer-reviewedCancer Biology