Yonglong Dang

Identification of an epigenetically and phenotypically distinct peritumoral glioblastoma cell population linked to inferior patient outcome

The paper identifies a distinct peritumoral glioblastoma cell population with unique epigenetic and phenotypic features associated with poor patient outcomes.

Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping

Spatial tri-omic sequencing (DBiT ARP-seq and DBiT CTRP-seq) and CODEX imaging map chromatin, RNA, and protein dynamics across mammalian brain development and lysolecithin-induced neuroinflammation.

Extrachromosomal DNA is associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma

The paper investigates extrachromosomal DNA (ecDNA) in gastric cardia adenocarcinoma, finding associations with chromothripsis, DNA damage, and prognosis based on oncogene amplicons.

Onset of differentiation is posttranscriptionally controlled in adult neural stem cells

The paper shows that posttranscriptional regulation, specifically translational repression, controls the onset of differentiation in adult neural stem cells.